Second placed KCCA FC will travel to Jinja to visit 13th placed Kyetume FC in their quest to maintain their charge for the title.
Kyetume FC are just a slot above the red line with only three points ahead of 14th placed Bright Stars.
The reverse fixture ended in a 5-2 win against the slaughters at the StarTimes Stadium in Lugogo.
KCCA FC youngster Sam Ssenyonjo who scored on his debut in the reverse fixture will unfortunately miss this game due to licencing issues.
Hassan Jurua and Jackson Nunda also remain sidelined while Sadam Juma has returned to full training but remains doubtful.
New signing Moses Aliro scored on his debut against CATDA FC in Uganda Cup and could be handed his first league appearance.
Kyetume skipper Vincent Kayizzi has his lincence issues sorted and he is expected to be unleashed against his former side.
Joel Mutakubwa and his defence line commanded by Jonathan Mugabi Dante must stand on alert to avert the possible danger to be caused by the KCCA attack.
KCCA FC are four points adrift the leaders Vipers and can reduce the gap to only one point incase they win while Kyetume will raise to 20 points but will change no position if they get maximum points out of this encounter.